Inonyanya Kushandiswa Antivenom MuIndia Haisi Kushanda Izvo
Inonyanya Kushandiswa Antivenom MuIndia Haisi Kushanda Izvo
Anonim

Huwandu hunotorwa nevaIndia vanorumwa nenyoka gore negore hunotyisa. Humwe hwerengedzo dzinoti vanhu vanosvika zviuru makumi masere nechimwe vanorumwa gore rega rega, zvichikonzera kufa kwevanhu vanosvika zviuru gumi nechimwe. Vamwe vanototi nhamba yevanhu vanofa yakakwira se50,000 pagore. Pasinei nenhamba yechokwadi, iyi mhedzisiro inotyisa inoita kuti India ive nyika yakaparadzwa zvakanyanya nekurumwa nenyoka pasi rose.

Kune marudzi anopfuura 270 enyoka muIndia. Panhamba iyi, vanenge makumi matanhatu vane huturu hwakanyanya. Pakati penyoka dzine njodzi muIndia pane Malayan Pit Viper, Banded Krait, Indian Cobra, Russell's Viper uye Saw-scaled Viper. Pakati pemhando idzi, "Big Four" nyoka dzine ngozi zvikuru iIndia Cobra, Krait, Russell's Viper uye Saw-scaled Viper.

Zvikonzero zvekufa kwakanyanya kusingagamuchirwe kubva pakunonoka kana kusasvika kwevakakuvadzwa kunzvimbo dzehutano mukati memaawa matanhatu akakosha kusvika pakushomeka kweantivenin uye kusatarisirwa kwakakwana panzvimbo yehutano. Zvino, zvinoita sekunge chikonzero chitsva chawedzerwa: antivenin inonyanya kushandiswa kurapa kurumwa nenyoka inonzi haishande pakurwisa Big Four.

MuIndia, mushonga wegoridhe-mwero mushonga unorwisa huturu hwakasanganiswa hweBig Four. Uku kurapwa kwakakosha kunogara kuchiponesa hupenyu uye kunoramba kuchidaro. Asi chidzidzo chitsva chakaburitswa kutanga kwaZvita muPLOS Neglected Tropical Diseases chinoratidza kuti antivenin iyi yegoridhe-yakajairwa inouya ipfupi ichirwisa uturu hwedzimwe nyoka dzekuIndia dzine kurumwa kwadzo kunouraya zvakaenzana.

Kartik Sunagar, munyori-mubatanidzwa wechidzidzo ichi uye nyanzvi yekushanduka-shanduka kuIndia Institute of Science muBangalore, akati panzvimbo yekunyanya kuvimba nemishonga yegoridhe, chinodiwa maantivenom akatarisana nenharaunda. Sunagar nechikwata chake vakawana antivenin inotengeswa zvakanyanya yakundikana kurwisa huturu kubva kumarudzi ese emhungu ine monocled, iyo Sind krait uye kuchamhembe kwevanhu ve common krait.

Akataura kuti huturu hwemhando imwe chete hunogona kusiyana pakati penzvimbo dzakasiyana dzenzvimbo. Mhuka dzenyoka dzinoparadzirwa zvakanyanya muIndia. Sunagar nechikwata chake vakawana uturu hweimwe monocled cobra yakanangana netsinga system. Nekune rimwe divi, uturu hwevamwe vanhu hwakapfuma muchetura unokonzera kukuvara kwesero nenyama. "Uturu hwenyoka dzemuno, dzine hutano hunofanirwa kushandiswa kugadzira maantivenin anozoshanda zvakanyanya mudunhu iroro," Sunagar akadaro.

Akawedzera mari yehurumende uye kutarisa kuchaita zvakawanda kubatsira kugadzirisa dambudziko iri. Sunagar nevamwe vake vava kushanda nevagadziri veantivenin kuti vagadzire uye vaedze maantivenini edunhu. Akataurawo zvidzidzo zvinoratidza maumbirwo ehuturu hwemarudzi enyoka anosiyana zvakanyanya.

"Tinobata kurumwa nenyoka sechimbichimbi chekurapa," Nick Casewell, anoshanda pahuturu hwemhuka paLiverpool School of Tropical Medicine muEngland, akadaro. "Asi chokwadi ndechekuti, kana ukarumwa nenyoka semhungu, unogona kutambura neurotoxic zvinokonzerwa nekufema mitezo, (uye) kana ukarumwa nenyoka yaRussell, unogona kunge uine zvakasiyana zvachose. ye syndromes senge kubuda ropa kana kubuda ropa kusagadzikana."

Kuedza kwakati kuri kuenderera pasirese kuvandudza marapirwo aripo ekurumwa nenyoka uye kuwana nzira dzekurapa. Sunagar, Casewell uye masayendisiti kubva kuKenya neNigeria chikamu chemubatanidzwa chiri kutsvaga kugadzira mhando nyowani yeantivenin kurwisa huturu kubva kuAfrica neIndia.

Chinangwa checonsortium ndechekugadzira marapirwo akananga kune chepfu muhuturu. Iyi cocktail yeakasarudzwa masoja ekudzivirira chirwere angangove akachengeteka kune varwere.

Zvikamu gumi neshanu muzana chete zvemasoja ekudzivirira chirwere ari muantivenin akananga kune chepfu, sekureva kwaCasewell. Mamwe ose anonangidzirwa kumaparasite kana kuti utachiona huri munzvimbo yenyoka.

Panzvimbo pekungotora masoja ekudzivirira chirwere kubva muropa remhuka, Casewell nevamwe vake vanounganidza masero anoagadzira vokura aya murabhoritari. Vanozoshandisa maseru aya kugadzira "library" yekugadzira yemasoja ekudzivirira chirwere.

"Tinogona kuzongosarudza masoja mashoma ekudzivirira ekudzivirira ehupfu hwakasiyana uye toshandisa iwo semushonga unoenderera mberi," akawedzera.

Yakakurumbira nenyaya