Viagra Obesity Treatment? Sildenafil Inopisa Mafuta Akawandisa muMice
Viagra Obesity Treatment? Sildenafil Inopisa Mafuta Akawandisa muMice
Anonim

Kurapa kweViagra kufutisa kunogona kunge kuri mumabasa- mushonga wekutengesa, wakanyatsosimbiswa mukurwisa erectile dysfunction, unogona kupisa mafuta zvakare. Chidzidzo chakabudiswa muna April 2013 edition ye FASEB Journal inoona kuti Viagra, inozivikanwawo se sildenafil, inogona kukurudzira kuora muviri nekusimudzira kuchengetedza kwehutano "mafuta matsvuku" pamutengo we "mafuta machena" asina kunaka.

"Pane kudiwa kuri kukura kwemishonga mitsva yekurwisa kufutisa," akadaro munyori anoshanda pamwe nekudzidza Dr. Alexander Pfeifer, weYunivhesiti yeBonn Biomedical Center muGermany, mune chirevo. "Kuwana mitsva mitsva yemishonga iripo, yakadai sesildenafil, mune adipose tissue inogona kubatsira kuvhara nguva kusvikira mishonga itsva yekurwisana nekufutisa yagadzirwa."

Brown mafuta anopa kupisa uye anoshingaira kupisa macalorie. Yepamusoro mazinga ebrown mafuta anosimudzira metabolism, kusiyana nemafuta machena, ayo anochengeta simba rekushandisa gare gare uye haanyanyi kubatsira nekukurumidza.

Ongororo yapfuura yakaratidza kuti sildenafil inhibits kuparara kwecyclic GMP (cGMP), messenger molecule mumasero emunhu anodzora kuyerera kweropa uye moyo nemoyo homeostasis. Zvichienderana nezvidzidzo zviripo pamasero ekusaina nzira, chidzidzo chechikwata cheGerman chekutsvagisa chakafunga kushandisa Viagra kuongorora kuti cGMP yakakanganisa sei kudzora kwemafuta mumakonzo.

Mushure mekurapa mbeva ne sildenafil, vatsvakurudzi vakacherechedza ketani chaiyo yezviitiko zvema molecular. Mune yakajairika mbeva kushanda, cGMP inoderedza mazinga epro-kuzvimba mahormone, ayo anotumira chiratidzo che "brown" yewhite adipocytes, kana masero emafuta. Mbeva dzakapiwa sildenafil dzakaita kuti mafuta machena aite shava mushure memazuva mashoma ekurapwa, nekukurumidza zvakanyanya kupfuura ayo asina sildenafil. Vatsvagiri vanotenda kuti mhedzisiro yacho yakakonzerwa neakakwira cGMP mazinga.

Vatsvakurudzi vakadzokorora izvo zvakawanikwa mumasero emafuta ari oga. Ivo vakaisa cGMP kune yega adipocytes, kwavakaonawo browning maitiro.

"Zviri pachena, ukuru hunokosha kana zvasvika pakurema kwedu," akadaro Dr. Gerald Weissmann, Editor-in-Chief weThe FASEB Journal, mukutaura.

"Ongororo dzakawanda dzinoratidza kuti kufutisa ingozi yechirwere chevanhu vose, uye kuti kufutisa ihosha. Kuwana kuti Viagra nemishonga yakafanana inogona kuchinja kuumbwa kwemafuta emuviri wedu kune zvakakosha zvikuru."

Vatsvakurudzi havaendi kusvika pakubvumirana neViagra yekurapa kufutisa- ukuwo maitiro e sildenafil pamakonzo akajeka, akawandisa uye varume vasina simba havafanire kutarisira kuuraya shiri mbiri nedombo rimwe chete.

"Mishonga iyi yakanyatsotsanangura njodzi / yekubatsira profiles uye inotenderwa kurapwa erectile kusagadzikana," akadaro Weissman. "Kumwe kutsvagisa kucharatidza kana ivo vanobatsira mukurapa girth kusagadzikana kwevanhu."

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