Chirwere cheshuga 2 Chirwere Chinobvumirwa neFDA; Zvimwe Zvidzidzo Zvekuchengetedza Zvichaitwa 'After-Market
Chirwere cheshuga 2 Chirwere Chinobvumirwa neFDA; Zvimwe Zvidzidzo Zvekuchengetedza Zvichaitwa 'After-Market
Anonim

Vatongi veUS vakabvumidza mushonga wekurapa chirwere cheshuga cherudzi rwechipiri svondo rino mushure mekuyedzwa kukuru kwekiriniki.

Chikafu neDrug Administration yakabvumidza Invokana, mushonga unoitirwa kushandiswa nekudya uye kurovedza muviri kuvandudza glycemic control muvakuru vane chirwere. Type 2 chirwere cheshuga chinokanganisa vamwe 24 miriyoni vekuAmerica uye inodarika 90 muzana yeUS chirwere cheshuga, sekureva kwaDr Mary Parks, mutungamiriri wechikamu chemetabolism uye endocrinology zvigadzirwa muFDA's Center for Drug Evaluation and Research.

"Invokana, kana canagliflozin, ndiyo yekutanga kurapwa kwechirwere cheshuga yakagamuchirwa mukirasi itsva yemishonga inozivikanwa se sodium-glucose co-transporter 2 (SGLT2) inhibitors," Parks akadaro mukutaura. "Tinoenderera mberi nekufambira mberi hutsva nemvumo yemakirasi matsva emishonga anopa mamwe marapirwo ezvimwe zvirwere zvisingaperi zvinokanganisa hutano hwevanhu."

Mushonga uyu unogadzirwa naJohnson & Johnson weJanssen Pharmaceuticals, Inc., weTitusville, N.J., uye unovhara kudzoreredzwa kweglucose neitsvo, kuwedzera kubuda kweglucose uye kudzikisa mazinga eglucose muropa mune vane chirwere cheshuga vakakwirisa mazinga eglucose muropa.

Vatsvakurudzi vakaedza kuchengeteka uye kushanda mumatambudziko mapfumbamwe emakiriniki ane huwandu hwe10, 285 varwere, vachiratidza kuvandudzwa kwekutonga shuga yeropa - hemoglobin A1c mazinga, kunyatsojeka - uye kutsanya plasma glucose, zvakare.

Mushonga uyu wakadzidzwa semushonga wakasarudzika uye musanganiswa nemamwe marapirwo echirwere, kusanganisira metformin, sulfonylurea, pioglitazone uye insulin. The akajairika divi migumisiro mushonga: vaginal mbiriso utachiona uye weti turakiti chirwere. Mimwe mhedzisiro inosanganisira diuretic effect, iyo inogona kukonzera kudonha kamwe kamwe muBP wakamira, izvo zvinogona kukonzera dzungu kana kupera simba.

Mushonga uyu unotakurawo njodzi yematambudziko akakomba, zvisinei, kusanganisira zvimwe zviratidzo zvekuwedzera sitiroko njodzi uye diki yakawedzera njodzi yekurwiswa kwemoyo mukati memwedzi wekutanga wekurapwa. Mushonga wacho wakasimudzawo cholesterol - yakanaka uye yakaipa - vaongorori vakati.

Zvakadaro, iyo FDA yakati njodzi yezvakanyanya mhedzisiro haina kujeka, ine iyo label isina yambiro yakadaro. Mutongi, zvisinei, anoda Johnson & Johnson kuti aite zvimwe zvidzidzo zvishanu, kusanganisira kuyedza kwekiriniki, kuti vaenderere mberi kuyedza kuchengetedza.

Yakakurumbira nenyaya