Masayendisiti Anodzivirira Kurasikirwa Kwetsandanyama kunyangwe Kusashanda
Masayendisiti Anodzivirira Kurasikirwa Kwetsandanyama kunyangwe Kusashanda
Anonim

Kana iwe uchida mamhasuru makuru pasina kushanda kunze, pane tariro. Mumagazini yaMarch 2012 yakadhindwa yeFASEB Journal, masayendisiti kubva kuYunivhesiti yeFlorida anoshuma kuti mhuri yeprotein transcription factor, inonzi "Forkhead (Fox0)" inoita basa rinokosha mukugadzirisa skeletal muscle mass. Kunyanya, ivo vakaona kuti kupindira nekuita kweizvi zvinyorwa zvinodzivirira kutambisa tsandanyama zvine chekuita negomarara uye sepsis, uye zvinotokurudzira kukura kwemhasuru. Kuwanikwa uku kungangove kwakakosha kune chero chirwere, mamiriro kana mararamiro anotungamira mukuparara kwemhasuru, kusanganisira kusazvidira.

"Kurasikirwa kwemasumbu kunobatsira zvikuru pakufa kwezvirwere," akadaro Andrew R. Judge, Ph.D., muongorori akabatanidzwa mubasa kubva kuDhipatimendi rePhysical Therapy paYunivhesiti yeFlorida muGainesville. "FoxO mapuroteni anogona kupa chinangwa chemishonga inotarisirwa kuderedza kupera kwemhasuru uye nokudaro kuvandudza mararamiro ehupenyu uye mararamiro evarwere vane zvirwere zvakasiyana-siyana."

Kuti awane kuwanikwa uku, Mutongi nevamwe vaaishanda navo vakavharisa basa re "Forkhead boxO" mapuroteni, kana "FoxO," mumhasuru yemaskeletal yemakonzo ane hutano, septic mbeva, uye mbeva dzine cancer. Kurasikirwa kwemasisita mashoma mune avo vane cancer uye sepsis kwakadzikira zvakanyanya nekudziviswa kweFoxO chiitiko. Mune hutano kutonga mhuka inhibiting FoxO chiitiko chakakonzera kuwedzera kwemhasuru sero saizi yakaitika semhedzisiro yeprotein synthesis.

"Hapana munhu anogona kuramba kuti muviri wemunhu waifanira kufamba, uye kufamba kazhinji," akadaro Gerald Weissmann, MD, Editor-in-Chief weFASEB Journal, "asi chokwadi ndechekuti vazhinji vedu hatifambi zvakakwana., kungave nekuda kwechirwere, kukuvara, kana kungoita basa rakabatikana.Kuwanikwa uku nderimwe danho rakakosha rekurapwa kwekuparara kwetsandanyama mugomarara, utachiona hwakanyanya kana kuchembera - kana kuchengetedza tsandanyama dzedu kubatsira kutarisana nezvipfuramabwe nemiseve yerombo rakanaka.."

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